Category Archives: Medicine

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Packing for a Spring Hut Trip

Another winter has come and gone, and now Spring is in Colorado. Which means Winter will be back a couple more times before the snow all melts.

We’ve organized a team of friends from San Francisco, Denver, and Colorado high country for a backcountry excursion to one of Colorado’s 10th Mountain Division huts. The Benedict huts, our dwelling for two nights tucked into the wilderness outside of Aspen, are almost 6 miles from the trailhead, with an elevation gain of over 2000 ft. : a formidable trek, even for the experienced. And experience in wilderness trekking is one thing, but altitude is a game-changer. We will be well over 8000 ft. long before we reach the huts, so preparation for such an undertaking requires as much attention to mental, physical and physiological condition as much as clothing, gear and rations.

Weather & Conditions

This has everything to do with the weather, so it’s important to be on top of tracking all the resources available to you. At the top of my list in this region is the Colorado Avalanche Information Center. They provide up-to-date reports for high-risk areas around the state according to a comprehensive and easy-to-understand rating system. When considering this information, I always remember that our trek will take us through several types of terrain, and thus, several types of conditions: in and out of trees, varying steepness and exposure (to sun, wind, precipitation, etc.), all kinds of microclimates and environments (wetlands, scree fields).

The Colorado Avalanche Information Center provides no shortage of visuals to aid your risk assessment.

As far as incoming weather patterns are concerned, one of the most popular and reliable forecasts endorsed by people who play outside in Colorado is Open Snow. Founding meteorologist Joel Gratz updates local forecasts regularly, and provides information on what to expect with the outdoor adventurers in mind.

For our upcoming hut trip, it looks like the storm we’re expecting will be warmer and milder than recent systems, with most of it heading toward the northern mountain region. That being said, however, I’m keeping in mind that any projected weather system can be just a few degrees colder, a few inches wetter, and a few miles closer and change conditions dramatically. So let’s talk about how we can anticipate this with …

Gear & Clothing

The Commute

In any season in Colorado, there are essential comforts I always pack to get me to and from any hut that requires a hike, and to keep me happy while I’m enjoying the site. Dead of Winter, Height of Summer alike, the sun and glare is liable to be more intense than anything you’ve ever experienced at sea-level, while at the same time, the temperature and lack of humidity can cool your body significantly, night or day. Depending on how strenuous the commute is or how active you intend to be even after arriving at your destination, you may be constantly shedding, then adding, then shedding, then adding layers, so keep it all very accessible.

For this particular trek, I’ll be in snow gear. Basically anything I’d wear snowboarding: snow pants, outer shell on top, hat, gloves. I want it to be warm and waterproof on the outside. Underneath this shell, I want layers that I can strip down to as soon as I start moving and sweating with a 40 -60 lb. pack on. Unless the storm turns out to be much more intense (in which case, I’ll keep the outer layers on), I expect my skin to be steaming, so I won’t want to be in much more than warm compression tights, a t-shirt, and a light pullover. Your outer shell is for blizzards and water-proofing, so whatever you are stripping down to should be significantly lighter. Also, sunglasses or goggles. The glare from snow is significant. I bring both, because goggles get way too hot while I’m trekking uphill.

Here’s the tricky part: What are you going to wear on your feet? This is where the weather forecast comes in. This time of year, after such a snowy winter, I’m expecting most of the trail to be covered in snow, and the storm moving in is likely to bring more. I will be scoping out the trail pre-storm, which will give me a much better idea of what to expect, but I’m preparing to have snowshoes or a split-board and skins strapped to my snowboard boots. Of course, skis with skins are another alternative. There is a very slim chance most of the snow on the trail will be melted down, in which case I would probably opt for waterproof boots instead, which I would expect to get pretty muddy.

Avalanche Gear

Whether it’s on the commute or while you explore terrain around the hut during your stay, there are some essentials you can pack for the worst-case scenario. I’ve gone into more detail in a previous blog, but standards that I will be keeping on me are a shovel, probe and beacon. But these tools are only a small part of avalanche preparedness. More important than the endless supply of technology you can invest in is knowing what conditions and natural phenomena to be aware of during your trek, and the Colorado Avalanche Information Center is a great place to start familiarizing yourself with these.

Cabin Comforts

There is only one limiting factor to this list, but it is considerable: how much you can carry. For six miles. Uphill. In snow.

Most of the huts in the 10th Mountain Division hut system are equipped with soft mattresses, small pillows, and blankets. The kitchens are stocked with utensils and dishes, there is toilet paper, paper towels, hand sanitizer and dish soap, as well as ample supplies of wood for burning in the wood stoves. So most of your weight will be food and drinks.

I always pack a sleeping bag and extra pillow, because the guaranteed warmth and comfort are worth it when you’ve spent your day being intensely active outdoors. And keep in mind you’ll want warm, dry layers to change into that you haven’t been hiking and sweating in all day. What do you want to be wearing when you’re lounging around the cabin reading, cooking, eating, playing cards, etc.? For me, this looks like socks, long underwear, a pullover and slippers that I can crush into my pack. And then what are you going to throw on when you have to go back outside into the dark cold of night to use the outhouse? Your Colorado uniform: a hoodie.

There won’t be running water, so you can’t expect to shower. When you’re in the wilderness for a long time and need to be discerning about how much weight you carry that isn’t food and water, bathing is of low priority. But for a short trip like this, I don’t mind bringing some form of wet wipes; they’re light-weight and take up very little space. Toothbrush and toothpaste should be obvious, though.

Medication & Acclimation

From climbing Mt. Fuji to Colorado’s 14er’s, I’ve noticed a lot of people bringing pressurized cans of oxygen. High altitude research has taught me just how temporary and unnecessary this trend is. Often, the most effective remedy for altitude sickness is 5 – 10 minutes on oxygen. I’m pretty sure you’ll blow through a whole can of gas-station aerosol oxygen before it does you any lasting good.

Avoid this by giving yourself time to acclimate before you get to extreme elevation. Ebert Family Clinic in Frisco, Colorado, specialists in high altitude research, always recommend keeping track of blood oxygen saturation with a pulse oximeter, and this is something small, inexpensive and very portable. Our team will be spending at least 24 hours at altitude before we embark on the trek to the hut. This way, members from lower elevations will have access to an oxygen concentrator to facilitate acclimation.

Physician and high altitude expert Dr. Christine Ebert-Santos recommends packing the following mediations for hut trips: Acetazolamide, Benadryl, Ibuprofen, an EpiPen, Acetaminophen, and topical antibiotic oinment. Of course, be aware of any allergies to medication in your party. It is also helpful to be aware of what symptoms you may expect to experience, should you start having trouble acclimating, including dizziness, nausea, hyperventilation, and fatigue.

Food & Water

This is where most of the weight you pack in will be. Again, no running water at the hut, so expect to boil all the water you need for drinking if you run out of what you bring. There are lots of compact water purification systems you can easily pack as well. For our six mile trek to the cabin, I will have a Camel Bak and a couple Nalgene-sized thermoses full of water tucked into my pack.

You don’t want to have to cook everything you bring, so snacks you can easily access and eat are essential, especially for the trail. For this particular hike, I expect to burn more calories more quickly than any other average day, so I want lots of nutrients per gram: pistachios, energy bars, jerky … And don’t underestimate the power of sugar and caffeine, this is precisely the kind of work your body acts quickly to convert these nutrients to energy for. And yes, I mean chocolate. (Fruit also contain a lot of valuable sugar, I’m told.)

While we’re at the cabin, we’ll have access to a propane stove, so we’ll be able to cook some hearty meals. Bacon, fruit, yogurt, bagels and cream cheese are all easy breakfast foods to pack. If you are fortunate enough to be on a hut trip with Dr. Chris herself, you will have pancakes at least once. It’s also easy enough to bring fixings for the most epic sandwich you’ve ever had: guacamole, sprouts, turkey, ham, greens, tomatoes, bread; and remember, it’s a good chance to justify all the calories you get from mayonnaise and mustard.

And speaking of calories and sugar, I feel like whiskey and beer were invented to accompany the warmth of a fire in a remote, mountain cabin. The good news is that you are sure to be carrying less out than you did in. The bad news is that hangovers are exacerbated by high altitude, so pay more attention to your consumption than you would at any lower elevation, and be sure to have plenty of drinkable water at hand.

Am I Ready?

Hut trips in Colorado are mentally and physically challenging, even in the best conditions. The more time you give yourself, the better. Know before you go and don’t go alone. And don’t be intimidated. I’ve successfully guided friends from sea-level who don’t consider themselves athletic to destinations well above the tree line without incident.

Always be checking in with your body, your team, and your environment.

Roberto Santos is from the remote island of Saipan, in the Commonwealth of the Northern Mariana Islands. He has since lived in Japan and the Hawaiian Islands, and has made Colorado his current home, where he is a web developer, musician, avid outdoorsman and prolific reader. When he is not developing applications and graphics, you can find him performing with the Denver Philharmonic Orchestra, snowboarding Vail or Keystone, soaking in hot springs, or reading non-fiction at a brewery.

Increasing the Altitude to Decrease the Symptoms of Parkinson’s Disease

By Jessica Thomas PA-S

 In May of 2009 Michael J Fox’s “Adventures of an Incurable Optimist” aired on ABC. This special chronicled his decision to battle the effects of his Parkinson’s disease with optimism and hope. During the production of this special he journeyed to the Kingdom of Bhutan. While in Bhutan, Michael J. Fox noted that his symptoms of Parkinson’s disease had almost completely vanished. 

 Bhutan lies between China and India, on top of the Himalayan Mountains. Bhutan is an extremely unique country since it is cut off from the rest of the world and has a desire to keep its culture unaffected by today’s modernization and globalization. Altitudes in Bhutan average 8-9,000 ft above sea level. When Fox’s parkinsonian symptoms decreased, he couldn’t help but wonder about the connection between the increased altitudes and the decrease of his symptoms. 

With more research into the topic it becomes apparent that Michael J. Fox was not the first person with Parkinson’s disease to notice a difference when in the high altitudes. According to Fred Ransdell, author of Shaky Man Walking, he has had two individual experiences where his tremors almost completely vanished. The first takes place whenever he is flying. Mr. Ransdell states that as the plane gains altitude he will remain completely asymptomatic until the plane lands. The second was when he was driving over a mountain pass at 9,000 feet elevation and he states that at that moment he noticed that his tremors were gone. How can this be? 

The first theory for why the increased altitude (>6,000 ft above sea level) decreases symptoms of Parkinson’s disease stems from the pH of our blood. When at higher altitudes we breathe faster and deeper in order to get enough oxygen into our lungs. When we breathe, our body discards carbon dioxide in proportion to oxygen we take in. Knowing this, it is understood that the increase in breathing also causes our body to get rid of more carbon dioxide from our blood which in turn will raise the blood pH making it more alkaline in nature. Naturally our blood is alkaline (approximately a pH of 7.3-7.4), otherwise death would ensue. Acids in our body are generally cell by-products, meaning that when our body is making energy or other necessities to life, they will give off acids. These acids are processed through the lymphatic system. When we have increased acids in our body the lymphatic system can get backed up. The back-up of acids in the body can cause stiffness, pain, and swelling. As the back-up worsens, deeper problems occur that affect the function of the cells and the tissues which can turn off hormone, steroid, and neurotransmitter production. Although this is an oversimplification of the process, it is easy to see that the more acidic the blood is, the more we may see increased symptoms of Parkinson’s disease. Correction of this acidosis is thought to preserve muscle mass in conditions like Parkinson’s and help with coordination. 

The second theory revolves around hypoxia and the main neurotransmitter that Parkinson’s disease effects. A study published in Springer titled Intermittent Hypoxia and Experimental Parkinson’s Disease found a link between hypoxia and the increase of dopamine synthesis. We know that atmospheric pressure reduces with altitude and with that so does the amount of oxygen. The reduction in the partial pressure of inspired oxygen at higher altitudes lowers the oxygen saturation of the blood which leads to hypoxia. But what does this have to do with parkinsonian symptoms? The results of this study revealed that a two-week course of intermittent hypoxia training in patients with Parkinson’s disease increased dopamine synthesis in old and experimental PD animals which restored the asymmetry of DA distribution in the brain. Parkinson’s disease is a progressive disorder that affects dopamine-producing neurons in the brain. When these neurons are destroyed, the production of dopamine severely decreases and we see symptoms such as tremors, slowness, stiffness, and balance problems

The Michael J. Fox Foundation for Parkinson’s Research received a research grant in 2018 to study the effects of altitude on Parkinson’s Disease. The study consists of two individual parts. The first part is a focused survey that asks individuals with Parkinson’s about their best and worst experiences with their symptoms during their travels in the last 2 years. The second part of the study will be an in-depth survey that with capture the travel experiences prospectively. 

Maybe we see the decrease in symptoms because of the hypoxia or maybe it is due to the increased pH of our blood, or maybe it is because of something we have yet to discover. With the new study from the Michael J. Fox Foundation on the horizon, answers to this question may be within our grasps. 

Jessica Thomas is a Physician Assistant student at Des Moines University in Iowa. Following graduation Jessica will be practicing family medicine in small town Iowa with an emphasis on preventative care and pediatrics. Over  the course of the last year she has had the joy of living and working in 6 different states around the country and has experienced many different climates and learned how to care for the ailments that occur in the different regions of the United States. When not at work or studying, you can find her reading on her porch swing, watching Hallmark movies in bed on Sunday afternoons, or spending time with her family and friends. 

References

F. R. (n.d.). Altitude and Parkinson’s disease. Retrieved from https://www.shakymanwalking.com/altitude-and-parkinson-s.html

Altitude in Bhutan. (n.d.). Retrieved April 12, 2019, from https://www.bhutantravelbureau.com/about-bhutan/township-altitudes/

Belikova, M. V., Kolesnikova, E. E., & Serebrovskaya, T. V. (1970, January 01). Intermittent Hypoxia and Experimental Parkinson’s Disease. Retrieved from https://link.springer.com/chapter/10.1007/978-1-4471-2906-6_12

Bloem, B. R., & Faber, M. J. (n.d.). Exploring the Effect of Altitude on Parkinson’s Disease. Retrieved April 12, 2019, from https://staging.michaeljfox.org/foundation/grant-detail.php?grant_id=1813

Ma, H., Wang, Y., Wu, J., Luo, P., & Han, B. (2015, September 01). Long-Term Exposure to High Altitude Affects Response Inhibition in the Conflict-monitoring Stage. Retrieved April 12, 2019, from https://www.nature.com/articles/srep13701

Parkinson’s and Nutrition. (n.d.). Retrieved from http://parkinsonplace.org/programs-services/parkinsons-and-nutrition/

Schwalfenberg, G. K. (2012). The alkaline diet: Is there evidence that an alkaline pH diet benefits health? Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195546/)

La Paz: Healthy Living At 12,000 feet

Dr Gustavo Zubieta-Calleja explains how lessons learned in La Paz can make space exploration easier

I just returned from the “Chronic Hypoxia” conference in La Paz, Bolivia at 12,000 feet elevation (3,640 m). The sponsor and organizers were Drs. Gustavo Zubieta-Calleja and his daughter Natalia Zubieta De Urioste who run the Institute of High Altitude Pulmonology and Pathology there. Presenters and attendees came from 16 countries covering topics ranging from molecular biology to genetics.
Dr. Zubieta previously published a scientific analysis of centenarians living at various altitudes. He compared Santa Cruz, Bolivia, at sea level, with La Paz/El Alto, each with populations of over three million, and found there are eight times more people over 100 years old at high altitude. (BLDE University Journal of Health Sciences, see blog post 1/5/18) Since his father Gustavo Zubieto Castillo founded the institute in 1970, they have been advocates of the health promoting effects of a low oxygen environment.
A presentation on “BioSpaceForming” even identifies chronic hypoxia as a “fundamental tool”, that “gives humans and other species an advantage on earth and beyond.” Dr Zubieta explained that the space station is engineered to have the barometric pressure (760 mmHg) and oxygen content of sea level. When the astronauts change into their space suits to work outside the ship they experience a pressure drop of over 200 mm Hg in a laborious process of donning the suit. Seeing that millions of inhabitants are healthy at 486 mm HG in Bolivia, he advocates that maintaining lower pressures and lower oxygen levels in the space station would be economical and promote the health of the astronauts. Several altitude scientists see this as a future that “uncouples biology and physics.

Life Threatening Causes of Low Oxygen At Altitude

Anyone who travels to areas of high altitude is at risk for high altitude pulmonary edema (HAPE). Classic HAPE symptoms include a dry cough and shortness of breath with activity; leading eventually to trouble breathing at rest. If left untreated, serious complications can occur. Many other conditions can mimic HAPE, and it is crucial for health care professionals to be able to distinguish between HAPE and other disorders that may cause similar symptoms. Illnesses that may present similarly to HAPE include pneumonia, a blood clot in the lung (pulmonary embolism), and chronic obstructive pulmonary disease (COPD) or asthma. Your health care provider will take a thorough history, but the following outlines the differences between HAPE and other similarly presenting conditions.

  • Pneumonia: In both HAPE and pneumonia, shortness of breath, fast breathing, and a fever occur. Normal oxygen saturations are above 90%, and if you have HAPE or pneumonia, these could be as low as 60 %. However, if you have pneumonia, you will feel a lot worse than if you have HAPE. HAPE typically responds to high flow oxygen and you will get better over a few hours. Whereas if you have pneumonia with low oxygen saturations, you will need immediate hospitalization.
  • COPD/Asthma: High altitudes may exacerbate your COPD or asthma. How providers tell the differences is through something called pulmonary function tests. This tests how well your lungs work. Your provider will have you breath into this device before and after being given albuterol. If your lung tests improve after the albuterol, then COPD or asthma are the more likely diagnosis. It is important to tell your provider if you have a history of COPD or asthma, and if you are a current or former smoker.
  • Pulmonary Emboli (PE): Patients with a blood clot in their lung typically have the same symptoms as HAPE but will sometimes also have chest pain when taking deep breaths. You may also have blood in your sputum and/or calf pain or swelling. You are more at risk for a PE if you have had a recent orthopedic surgery (such as a hip or knee replacement), you have an irregular heart rate, have a clotting disorder, smoke, or are on birth control. If you have these risk factors and additional symptoms, your provider may order a lab test called a d-dimer  and a chest CT scan to help distinguish between a blood clot or HAPE.

If you are experiencing any of these symptoms, it is important to go see a health care provider immediately. A thorough history and exam will help aid in the correct diagnosis and prevent any potential complications. And most importantly, will help you get back on track to enjoy your high-altitude vacation and living!

Miranda Bellantoni, FNP-Student

  1. Luks AM, Swenson ER, Bärtsch P. Acute high-altitude sickness. Eur Respir Rev 2017; 26.
  2. UpToDate. Distinguishing HAPE from Pneumonia 2018.
  3. Brusasco V, Martinez F. Chronic obstructive pulmonary disease. Compr Physiol 2014; 4:1.

The Mitochondrial advantage at altitude

Dr. Deborah Liptzen, pediatric pulmonologist from Children’s Hospital of Colorado,

Presents a talk on high altitude to the Ebert Family Clinic staff

I learned several new facts about adaptation to altitude that make us better athletes. First, our muscles have more capillaries to deliver blood to the cells. Second,  the cells have more mitochondria which are organelles involved in the chemistry of respiration and energy production.

Other ways our bodies respond to altitude include: increased breathing rate (instant), increased red blood cells (peaks in three months), hemoglobin in red cells holds on to more oxygen, and blood vessels in the lungs constrict (immediate).It is this constriction of blood vessels in the lungs that can go haywire putting pressure on the capillaries causing fluid leaks that lead to pulmonary edema or HAPE.

Altitude research partnership with University of Heidelberg and University of California in San Diego

Two of the most prominent centers for altitude research in the world are University of Heidelberg, led by Peter Bartsch MD and                                                                                                               University of California in San Diego, with John West MD.

Dr Christine Ebert-Santos met with five of their affiliated researchers while in San Diego where she presented her case on                                                                                                                    trauma and HAPE at the American Thoracic Society conference.

They are interested in partnering with Ebert Family Clinic for a study related

to the genetics of high altitude, using our area as an intermediate altitude location.

Photo of Dr. Chris with UCSD staff  Tatum Simonson PhD, facing, Jeremy Orr MD, behind her,

Jeremy Sieker MD PhD candidate from Colorado, and University of Heidelberg staff  Heimo Mairbaurl PhD and Christina Eichstaedt PhD

It’s so exciting to be CITED!

Today I opened the March 2018 issue of the Journal of High Altitude Medicine and Biology.

What a surprise!

My publication  was cited in an article on pulmonary edema in children written by professors in the pulmonary department at Children’s Hospital of Colorado!  This is actually the first indication I’ve had that anyone beside me believes in the entity I called Mountain resident HAPE in the article published in the same journal last September.

Dr. Liptzin and her colleagues wrote, “We briefly describe high-altitude illnesses and propose recommendations for evaluation and treatment of HAPE in children as well as investigate the underlying contributors to HAPE. We discuss high-altitude resident pulmonary edema (HARPE), a new entity (Ebert-Santos, 2017). We will also highlight areas for further research.” The authors do not recommend prophylactic treatment for HAPE. Rather they recommend that when symptoms develop, supplemental oxygen be applied and  descent to lower altitude.

Pediatrics Gun Storage Practices

The American Academy of Pediatrics published a new study titled “Firearm Storage in Homes with Children with Self-Harm Risk Factors.” The conclusion of this article was that parent’s decision to have firearms in the home as well as their storage practices were not influenced by the presence of a child with a mental health condition in the home. The study was comprised of a web-based survey, which was completed by parents of 3,949 households in the US. The results showed that approximately 42% of households that contained children confirmed having a firearm in the house. This percentage did not change when comparing household in which children with mental health reside to those whose children had no mental health issues. The study also showed that of those parents/ caregivers who own firearms only 1 in 3 stored all firearms locked and unloaded. This ratio did differ between households that contained children with mental health issues versus those that did not.

This study led me to question the role of pediatrics in determining the ownership and storage of firearms in homes with children. At every well child visit for children above a certain age we ask if there are any firearms in the house and if so, how are they stored. I found myself wondering “Have studies shown a decrease in injury by firearms following pediatrician intervention and education?” A study published in 2000 concluded that “a single firearm safety counseling session during well child care combined with economic incentives to purchase safe storage devices, did not lead to changes in household gun ownership and did not lead to statistically significant overall changes in storage patterns.” However a randomized controlled trial published more recently, in 2008, concluded that a brief office-based violence prevention approach resulted in increased safe firearm storage.

The American Academy of Pediatrics first issued guidelines in 1992 noting that the safest home for a child is one without firearms. These guidelines also note that if firearms are going to be in households they should be locked and unloaded with ammunition stored separately. I grew up in a house of avid hunters and gun owners and I can just hear them saying, “What good is a gun in the case of an intruder if it is not immediately accessible?” One study in the Journal of Trauma found that “guns kept in homes are more likely to be involved in a fatal or nonfatal accidental shooting, criminal assault, or suicide attempt than to be used to injure or kill in self-defense.” This article claims that the benefit of having a gun in the house for self-defense does not outweigh the risk of accidental injury by that same “protective” weapon. Other’s who advocate for firearm use and ownership claim that if children are properly educated and trained in gun safety there would be less accidental shootings. However, one study published in 2002 had children participate in a weeklong firearm safety program on reducing children’s play with firearms. Following this training period the children were exposed to an unloaded firearm. 53% of the children played with the gun as if it was a toy gun. This study cast doubt on the effectiveness of skills-based gun safety programs for children.

I recognize that it would be naïve of me to think that every gun owner with children in the house is going to forfeit his or her right to their firearms because of this data. That is why there are important organizations such as Project Childsafe (http://www.projectchildsafe.org/parents-and-gun-owners) that cater towards gun owners. This organization provides comprehensive information about gun safety in the home and offers free resources such as cable-style gunlocks to further protect children in their homes.

Jocelyn Rathbone PA-S

References:
Scott J, Azrael D, Miller M. Firearm Storage in Homes With Children With Self-Harm Risk Factors. Pediatrics 2018 March; 141(3): e20172600. Retrieved March 11, 2018.
Kellermann AL, Somes G, Rivara FP, Lee RK, Banton JG. Injuries and deaths due to firearms in the home. J Trauma. 1998 Aug; 45(2):263-267. Retrieved March 11, 2018.
Barkin SL, Finch SA, Ip EH, Scheindlin B, Craig JA, Steffes J, Weiley V, Slora E, Altman D, Wasserman RC. Is office-based counseling about media use, timeouts, and firearm storage effective? Results from a cluster-randomized, controlled trial. Pediatrics. 2008; 122(1): e15. Retrieved March 11, 2018.
Grossman DC, Cummings P, Koepsell TD, Marshall J, D’Ambrosio L, Thompson RS, Mack C. Firearm safety counseling in primary care pediatrics: a randomized,  controlled trial. Pediatrics. 2000; 106(1 Pt1): 22. Retrieved March 11, 2018.
Hardy MS. Teaching firearm safety to children: a failure of a program. J Dev Behav Pediatr. 2002;23(2):71. Retrieved March 11, 2018.
Gill AC, Wesson DE. Firearm Injuries in Children: Prevention. UptoDate. Literature review current through Feb 2018. Last updated March 14, 2018. Retrieved March 11, 2018.

Trauma Related High-Altitude Pulmonary Edema

HAPE Poster

Dr. Chris will be presenting this poster at the American Thoracic Society International Conference in San Diego in May of this year! This is an exciting opportunity that will spread knowledge of high altitude medicine with the leading researchers in the field. In addition, she hopes to have this case study published to raise awareness among other healthcare providers practicing at any altitude about the potential health complications associated with rapid changes in elevation.

Katie Newton, PA-S
University of St. Francis
Albuquerque, NM

 

A Query on Mt Quandary

A personal story of acute mountain sickness (AMS)

Disturbing the “Locals”

“Race ya down”, my friend Liz took off from the summit of Mt. Quandary. Ahead of us stood a 2 mile scrabble through a boulder field with a 1 mile decent down a winding trail through the forest where we would descend from 14,265’ to 10,850’. In my experience, a 6 mile hike with 3,400 vertical feet was no feat. However, something was different as we approached the cars at the end of the hike. I noticed the start of a headache and I held onto the car to keep myself from swaying while taking off my boots. Thinking this was merely dehydration I finished my 3 liters of water – but that did not help. Once in the car my head continued to throb as we drove over Hoosier pass. Incoherently I mentioned that we should stop for Gatorade but the 64 oz of Gatorade did not abate my symptoms. In fact they worsened, my symptoms included severe dizziness, nausea, and a pounding headache. While my memory was hazy I knew this was not dehydration, maybe this was acute mountain sickness? But how could it be? I was in shape, lived at 5,400’, and this was my 5th 14er that summer. Was it possible to have AMS on the same peak I had climbed just weeks prior?

Standing on the summit of Mt. Quandary

My name is Chris Whitcomb and I am a 3rd year PA student at the University of Colorado. This story is all too familiar for anyone who spends time at elevation. Thankfully by the time we hit Idaho Springs, 7,526’, my symptoms dramatically improved. After reviewing my case and talking it over with my peers I believe that I developed AMS with some elements of HACE mixed in. A quick calculation of the Lake Louise Score came in at 6, which would classify this episode as “severe AMS”.

Who is most susceptible to AMS?

A prospective study analyzed a total of 11,182 workers on the Quighai-Tibet railroad in Tibet. This study identified 6 independent risk factors for AMS such as: rapid ascent to elevations above 3500 m (11482’), sea-level or lowland newcomers, young people of age, heavy physical exertion, obesity, or SaO2 below 801 Another study in 2013 looked into various other predictive indexes for AMS and found that the level of activity (higher activity) and sex (male>female) lead to increased odds of AMS 2. A quick review of the above criteria showed that I was the perfect demographic for AMS. I am a young male who was exerting myself physically at altitude.

Will this stop me from hiking at elevation?

Not one chance! Last summer alone my wife and I backpacked and hiked over 250 miles in Colorado. Since the incident I now make sure that I have the ability to seek lower elevation if needed during all our outdoor adventures. I also pay close attention to how I am feeling as we ascend.

Should I take acetazolamine/Diamox before backpacking trips because of my past AMS episode?

A meta-analysis in 2015 looked at 7021 individuals to see if a past episode of AMS warranted medication to prevent future AMS episodes. Interestingly enough they found that the literature did not support it. This was in part due to the sporadic nature of AMS 3I personally do not take a prophylactic medication before hiking at elevation, but this would be a great conversation to have with your medical provider if you are at all concerned.

Chris Whitcomb, PA-S3
University of Colorado
Class of 2018

References

  1. Wu TY, Ding SQ, Liu JL, Jia JH, Chai ZC, Dai RC. Who are more at risk for acute mountain sickness: a prospective study in Qinghai-Tibet railroad construction workers on Mt. Tanggula. Chin Med J. 2012;125(8):1393-400.
  2. Beidleman BA, Tighiouart H, Schmid CH, Fulco CS, Muza SR. Predictive models of acute mountain sickness after rapid ascent to various altitudes. Med Sci Sports Exerc. 2013;45(4):792-800.
  3. Macinnis MJ, Lohse KR, Strong JK, Koehle MS. Is previous history a reliable predictor for acute mountain sickness susceptibility? A meta-analysis of diagnostic accuracy. Br J Sports Med. 2015;49(2):69-75.